The Effectiveness of 675 nm Wavelength Laser Therapy in the treatment Androgenetic alopecia among Indian patients. (Preprint)

Abstract

Androgenetic alopecia (AGA) is the most prevalent cause of male/female hair loss around the world.

the purpose of this study was to evaluate the efficacy of laser stimulation with 675 nm wavelength for the treatment of AGA in male and female Indian patients.

a total of 20 Indian healthy patients aged from 23 to 57 years and who presented a grade of Alopecia stage I to stage V, underwent one single pass of 675 nm laser in scalp area twice a week for a total of 8 sessions, followed by once a week for 4 sessions and once in 2 weeks for 2 sessions. At the end of treatment protocol patients have completed 14 laser sessions. Macro and Dermatoscopical images have been acquired at T0 (baseline) and T1 (4 months). The areas of scalp including vertex, frontal and parietal were evaluated. Many parameters were analysed including hair count and hair density of terminal, mean thickness, vellus follicules, total follicular units, units with 1 hair or 2,3,4 or more than 4 hairs, units density and average hair/unit.

Macro images and dermatoscopic evaluation show good improvement over the entire treated area, with a clear increase in number of hairs and thickened hair. General parameters such as hair count and hair density show a percentage increase of around 17%. The hair mean thickness parameters shows a significant (p<0.05) percentage increase of 13.91%. Similar results were obtained for terminal hair and vellus: hair count and hair density terminal significantly (p<0.05) increased of 17.45%, hair count vellus significantly (p<0.05) increased of 16.67% and hair density vellus significantly (p<0.05) increased of 16.61%.

The study findings demonstrate that the 675 nm laser system improves AGA in Indian subjects, facilitating the anagen phase and improving the hair density and other positive hair parameters.