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This study investigates the application of ChatGPT, an artificial intelligence tool, in providing information on skin toxicities associated with cancer treatments. The study utilized 40 questions, split between patient-oriented and oncologist-oriented, to assess the accuracy and comprehensiveness of ChatGPT's responses. Three oncodermatology specialists from a New York tertiary academic institution evaluated the responses, which showed high accuracy and comprehensiveness. However, the reading level of the responses was at the college level, potentially limiting their accessibility to patients. The study highlighted that while ChatGPT can serve as a valuable resource for clinicians, its use for patient education requires careful consideration due to the complex nature of the information provided. There were also some concerns about the need for evidence-based and up-to-date clinical recommendations. Despite these challenges, ChatGPT demonstrates potential as a supplementary tool for oncologists and dermatologists in managing and educating about cancer treatment-related skin toxicities.