Influencing factors associated with facial skin problems due to wearing masks during COVID-19 in China (Preprint)

Abstract

Background: Wearing a mask is one of the most effective measures to prevent COVID-19 virus infection and it is not yet clear what potential factors may be associated with facial skin problems while wearing masks.

Objective: seek most suitable mask-wearing habits for public to avoid facial skin problem.

Method: A cross-sectional survey was conducted through online and offline questionnaires on patterns of mask wearing and facial skin problems during COVID-19 from May 30-July 1, 2020. Multivariable regression was used to explore the potential factors associated with skin problems. We also recruited 19 subjects and compared the differences in their facial microbiomes before and after wearing masks.

Results: A total of 4385 valid questionnaires were finally analyzed and 1323 (33.1%) participants reported having facial skin problems while wearing masks. The risk factors associated with skin problems were having a history of facial skin problems (OR: 3.25, 95% CI: 2.80-3.76), facial skin allergies (OR: 1.37, 95% CI: 1.20-1.56), face washing frequency (≥3 times per day) (OR: 1.61, 95% CI: 1.07-2.43), daily sleep time <6 hours (OR: 2.38, 95% CI: 1.81-3.13), and average time spent wearing masks uninterruptedly ≥6 hours (OR: 1.67, 95% CI: 1.24-2.25). The analysis of the facial microbiome revealed that the abundance of Prevotella and Hemophilus decreased, and the functional pathway associated with cytochrome c was more predominant with the prolongation of wearing time.

Conclusion: The habit of wearing a mask and life behavior affect the occurrence of skin damage. Suitable mask types and mask-wearing habits should be recommended to avoid facial skin problems.

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