Longitudinal Evaluation of an Integrated Post–COVID-19/Long COVID Management Program Consisting of Digital Interventions and Personal Support: Randomized Controlled Trial (Preprint)

Author:

Derksen ChristinaORCID,Rinn RobinORCID,Gao LinglingORCID,Dahmen AlinaORCID,Cordes CayORCID,Kolb CarinaORCID,Becker PetraORCID,Lippke SoniaORCID

Abstract

BACKGROUND

The postacute COVID-19 syndrome (PACS) can be addressed with multidisciplinary approaches, including professional support and digital interventions.

OBJECTIVE

This research aimed to test whether patients who received a health care facilitation program including medical internet support from human personal pilots and digital interventions (intervention group [IG] and active control group [ACG]) would experience fewer symptoms and have higher work ability and social participation than an untreated comparison group (CompG). The second objective was to compare the impact of a diagnostic assessment and digital interventions tailored to patients’ personal capacity (IG) with that of only personal support and digital interventions targeting the main symptoms (ACG).

METHODS

In total, 1020 patients with PACS were recruited. Using a randomized controlled trial design between the IG and the ACG, as well as propensity score matching to include the CompG, analyses were run with logistic regression and hierarchical-linear models.

RESULTS

Symptoms decreased significantly in all groups over time (βT1-T2=0.13, <i>t</i><sub>549</sub>=5.67, <i>P</i>&lt;.001; βT2-T4=0.06, <i>t</i><sub>549</sub>=2.83, <i>P</i>=.01), with a main effect of the group (β=–.15, <i>t</i><sub>549</sub>=–2.65, <i>P</i>=.01) and a more pronounced effect in the IG and ACG compared to the CompG (between groups: βT1-T2=0.14, <i>t</i><sub>549</sub>=4.31, <i>P</i>&lt;.001; βT2-T4=0.14, <i>t</i><sub>549</sub>=4.57, <i>P</i>&lt;.001). Work ability and social participation were lower in the CompG, but there was no significant interaction effect. There were no group differences between the IG and the ACG.

CONCLUSIONS

Empowerment through personal pilots and digital interventions reduces symptoms but does not increase work ability and social participation. More longitudinal research is needed to evaluate the effects of a diagnostic assessment. Social support and digital interventions should be incorporated to facilitate health care interventions for PACS.

CLINICALTRIAL

ClinicalTrials.gov NCT05238415; https://classic.clinicaltrials.gov/ct2/show/NCT05238415.

INTERNATIONAL REGISTERED REPORT

RR2-10.1186/s12879-022-07584-z

Publisher

JMIR Publications Inc.

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3