Spatiotemporal trends in the global burden of cervical cancer attributable to smoking from 1990 to 2019. (Preprint)

Author:

Yuan Ruixia,Ren Fang,Xie Yingying,Li Kaixing,Tong Zhuang

Abstract

BACKGROUND

Cervical cancer is the fourth most common cause of cancer death in women worldwide. Research on the burden of cervical cancer attributable to smoking is lacking.

OBJECTIVE

In this study, we used data from the Global Burden of Disease Study (GBD) to estimate the global burden of cervical cancer attributable to smoking from 1990 to 2019 and describe changes in this burden over time.

METHODS

We estimated spatiotemporal trends in the burden and mortality of cervical cancer attributable to smoking at the global, regional, and national levels. The data were obtained from the Global Burden of Disease Study (GBD) website. Age-standardized rates (ASRs) were used to facilitate comparisons in the burden at different levels. The estimated annual percentage change (EAPC) was used to assess trends in the ASR of mortality (ASMR) and ASR of DALYs (ASDR). Pearson’s correlation analysis was used to evaluate the correlations between the sociodemographic index (SDI) and ASRs.

RESULTS

From 1990 to 2019, the burden showed a decrease trend around the world, and EAPCs of ASMR and ASDR were -2.11 (95%CI: -2.16, -2.06) and -2.22 (95%CI: - 2.26, -2.18), respectively. In all 204 countries, 10 countries showed upward trends, 14 countries showed stable trends. Pearson’s correlation analysis revealed a significant negative correlation between the SDI and the ASRs of cervical cancer attributable to smoking.

CONCLUSIONS

An increase in the absolute number of cervical cancer cases attributable to smoking and a decrease in the time trend of the burden of cervical cancer attributable to smoking were observed in the whole population, and differences in these variables were also observed between countries and regions. More attention should be paid to cervical cancer prevention and screening in smoking women, especially in low- and middle-income countries.

Publisher

JMIR Publications Inc.

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