A Systematic Review and Meta-analysis of the Prevalence of Schizophrenia in China from 2000 to 2020 ABSTRACT Background The prevalence of schizophrenia is influenced by many factors. The rapid development of China's recent development may have an impact on the incidence rate of schizophrenia.To understand the prevalence of schizophrenia and the trend of nearly twenty years in China, providing scientific basis for early prevention and treatment by meta-analysis. Methods A systematic literature retrieval published from 2000 to 2020 in China was conducted by using Chinese database. The Joanna Briggs Institute (JBI) was used for assessment of literature quality.The Chinese schizophrenia prevalence and it’s subgroup analyses,including g (Preprint)

Author:

Chen HaihanORCID

Abstract

BACKGROUND

The prevalence of schizophrenia is influenced by many factors. The rapid development of China's recent development may have an impact on the incidence rate of schizophrenia.To understand the prevalence of schizophrenia and the trend of nearly twenty years in China, providing scientific basis for early prevention and treatment by meta-analysis.

OBJECTIVE

To understand the prevalence of schizophrenia and the trend of nearly twenty years in China, providing scientific basis for early prevention and treatment by meta-analysis.

METHODS

A systematic literature retrieval published from 2000 to 2020 in China was conducted by using Chinese database. The Joanna Briggs Institute (JBI) was used for assessment of literature quality.The Chinese schizophrenia prevalence and it’s subgroup analyses,including gender and regions was analyzed with Stata16.0. The literature publication bias was evaluated by Egger testing and funnel graph.The sensitivity analysis was also done by eliminating one by one.

RESULTS

Twenty-eight articles were included. The total sample size was 76273830. The Chinese Schizophrenia prevalence was 3.72 ‰ (95%: 3.30 ‰ - 4.22 ‰). Subgroup analysis showed no significant difference in the schizophrenia prevalence between genders(P>0.05) ,among rural and urban(P>0.05), between the years of the survey(P>0.05). The related age range of highest prevalence of schizophrenia was 35-64 years old.

CONCLUSIONS

The Chinese schizophrenia prevalence is 3.72 ‰. The schizophrenia prevalence is no difference with genders,urbancity.There was no significant change in prevalence of schizophrenia in the last twenty years.The related age range of highest prevalence of schizophrenia was 35-64 years old.The both epidemiology and systematic review are the way to get prevalence of schizophrenia.

CLINICALTRIAL

N/A

Publisher

JMIR Publications Inc.

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