BACKGROUND
Wide-ranging patient recruitment not restricted to the location of the investigator will provide a better representation of the patient population in clinical studies.
OBJECTIVE
To assess the feasibility of a broad online recruitment strategy in an 8-week observational study of 500 study participants with psoriasis and healthy controls from locations remote from the investigator, and to assess the cost associated with each participant.
METHODS
An online team in Denmark recruited patients with psoriasis and healthy controls using Google and Facebook advertisements and posts to Facebook groups. All individuals were screened online, and patients diagnosed with psoriasis were included. Questionnaires regarding itch and sleep were completed by both groups at inclusion, week four, and week eight.
RESULTS
During a two-week recruitment period, 12,887 unique advertisement views were registered, and 839 participants were enrolled, of which 507 completed the study (220 with psoriasis and 287 healthy controls) with a retention rate of 60.4%. Participants were recruited from 11 different countries on four separate continents, mainly from the United States, Canada, and the United Kingdom. The recruitment rate was 59.9 participants per day and the conversion rate was 57.2%. Recruitment costs were $13 per enrolled participant and $22 per participant completing the study.
CONCLUSIONS
It is feasible and rapid to recruit a large number of participants from locations different from the investigator and to retain patients in an observational study with no visits to a clinical site at low costs.