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The rapid advancements in Artificial Intelligence (AI), Augmented Reality (AR), and Virtual Reality (VR) technologies present significant opportunities for the healthcare industry. This paper explores the development and optimization of hybrid business models that leverage the combined potential of AI, AR, and VR in healthcare. We examine the synergies and complementarities of these technologies, focusing on their ability to enhance diagnostics, personalized treatment, and medical training. Furthermore, we discuss implementation challenges, including technological, organizational, and cultural barriers, as well as data privacy, security, and regulatory compliance issues. Drawing from case studies of successful hybrid business models in healthcare, we analyze the factors contributing to their success and provide insights for other healthcare organizations and technology companies. Finally, we offer recommendations for creating and optimizing hybrid business models, addressing implementation challenges, and fostering collaboration among stakeholders. Our findings contribute to the literature on AI, AR, and VR in healthcare and provide practical implications for healthcare organizations and technology companies seeking to innovate in this rapidly evolving field.