Author:
Chowdhury Md. Rayhan,Islam Shirmin,Matin Mohammad Nurul
Abstract
A sudden health crisis has shut down the entire world for almost a year due to a new virus called Covid-19 and thus the WHO has declared the COVID-19 as a pandemic disease. As vaccines stimulate the immune system to fight against future infections, thereby conferring immunity, so far, vaccine development in a race throughout the world. Therefore, disseminating the overview of the vaccine development at present with their critical situation for COVID-19 is the aim of this review. The world is looking eagerly for a potential vaccine candidate that can save every life. Here, we reported the overview of the possible types of vaccines against Covid-19 as well as a glimpse of vaccine race with different phases of clinical trial data, comparison of the rate of success of phase-III clinical trials and their safety, and drawbacks with the present status. We have studied literature from clinical trial data of respective vaccine candidates published in the journals and collected data from databases dedicated to corona vaccine and the vaccine company's website to enrich our review and aiming to focus on clinical trial data stages, how consequences it faces, and how to position it belongs towards a successful vaccine candidate.
Keywords: COVID-19, SARS-CoV-2, COVID-19 vaccine, Clinical trial.
Publisher
Society of Pharmaceutical Tecnocrats
Reference49 articles.
1. 1. Rabi FA, Al Zoubi MS, Al-Nasser AD, Kasasbeh GA, Salameh DM. Sars-cov-2 and coronavirus disease 2019: What we know so far. Pathogens 2020; 9(3). https://doi.org/10.3390/pathogens9030231
2. 2. Hu B, Ge X, Wang LF, Shi Z. Bat origin of human coronaviruses Coronaviruses: Emerging and re-emerging pathogens in humans and animals Susanna Lau Positive-strand RNA viruses. Virol J 2015; 12(1). https://doi.org/10.1186/s12985-015-0422-1
3. 3. Fani M, Teimoori A, Ghafari S. Comparison of the COVID-2019 (SARS-CoV-2) pathogenesis with SARS-CoV and MERS-CoV infections. Future Virol 2020; 15(5): 317-323. https://doi.org/10.2217/fvl-2020-0050
4. 4. Park SE. Epidemiology, virology, and clinical features of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2; Coronavirus Disease-19). Clin Exp Pediatr. 2020; 63(4):119-124. https://doi.org/10.14776/piv.2020.27.e9
5. 5. Pyrek K. 100 Years after the Spanish Flu: Lessons Learned and Challenges for the Future. Infection Control Today. 2018; 11. https://www.infectioncontroltoday.com/view/100-years-after-spanish-flu-lessons-learned-and-challenges-future
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献