OCULAR INSERETS AS A MODERN THERAPY TREND IN OPTHALMOPATHOLOGY

Abstract

Ocular insert (OI) has its wide recognition and importance from the 19th century around the world, the use of this dosage form in clinical practice was distributed throughout the USSR. The key issue covered in this review is the development of the ocular insert and their testing by specific parameters of quality. It is important to choose the right excipients and standardize ocular inserts according to pharmacopoeia articles (thickness, pH, biodegradation time). It is also important to control those indicators that increase patient compliance. Technology of solid dosage form consists of several stages: mixing, drying and cutting with packaging in primary polymer packaging. So the manufacturer does not need highly specialized equipment and staff skills. Based on this information, we can concluded that ocular inserts are promising and actively researched dosage form, which in the future, could fully complement or replace the medical drugs traditionally used in ophthalmology.