A REVIEW ON CHITOSAN-BASED MATERIALS AS POTENTIAL WOUND DRESSING MATERIALS

Abstract

This review article aimed to study chitosan as a material based in wound dressing preparation. The method in this review is the approximation method. The articles were obtained from national and international journals such as Scopus, PubMed, and Google Scholar by using the keywords "Chitosan", "Wound Healing", and "Biomedical Application". The inclusion criteria of the article are: national and international journals and books contains chitosan as, published in the last ten years, and not review article. The final articles used in this review are 29 articles that studying the use of chitosan as wound dressing material. The combination of chitosan with some polymer, ion and other materials resulting the chitosan-based materials namely nanofibrous membranes, composites sponge, polyelectrolyte complex, and composites, that used in topical preparation such as membranes, fibers, sponge, film, and gel. Thus, the modified of chitosan wound healing preparation resulting in the improve of healing activity of each preparation from. This review summarizes chitosan application in wound healing. Several studies were proposed the porous structure of chitosan-based materials lead the improvement of healing activity.