ANTIOXIDANT ACTIVITY OF EFFERVESCENT GRANULES FROM KIRINYUH LEAVES (CHROMOLAENA ODORATA (L.) R. M. KING and H. ROB) AND LEAF OF MAREME (GLOCHIDION ARBORESCENS BLUME)

Abstract

Objective: The objective of the study was to prepare and evaluate the formulation of the granules effervescent from kirinyuh and mareme leaves as an antioxidant. Methods: The method of making granules with the wet granulation method. The granulation method was used for making granules, meanwhile, the evaluations of the granules was included organoleptic tests, water content, solubility time, pH of the preparation, compressibility, flow time angle of repose and antioxidant activity. Results: The results showed that combination of kirinyuh and mareme as effervescent showed fulfilled all the test criteria, however, demonstrated weak antioxidant activity. Conclusion: The three formulations of effervescent granule preparations from kirinyuh leaves and mareme leaves have very weak antioxidant activity