Author:
MEENA RAKESH KUMAR,AGARWAL DEEPAK,PABRI MANISH
Abstract
Common variable immunodeficiency syndrome (CVID) is a disorder characterised by reduced levels of IgG, IgA and/or IgM, and recurrent bacterial infections. Sinopulmonary infections, gastrointestinal infections. It is commonly seen in association to immunodeficiency states such as CVID, IgA deficiency and chronic infections due to Giardia lamblia and Helicobacter pylori. We report a case of CVID with low CD 4 counts having recurrent diarrhoea, weight loss, anasarca and Hypoproteinaemia.
Publisher
Innovare Academic Sciences Pvt Ltd
Reference8 articles.
1. Fischer A. Primary immune deficiency diseases. In: Loscalzo J, Fauci A, Kasper D, Hauser S, Longo D, Jameson JL. editors. Harrison’s principles of internal medicine. 21st ed. New York: McGraw-Hill Education; 2022. Available from: https://accessmedicine.mhmedical.com/content.%20aspx?aid=1190522036
2. Moore D, Dias F, Esberard E, Mugayar J, Costa M, Pestana S. Common variable immunodeficiency misdiagnosed as crohn disease. World Allergy Organ J. 2015;8:A267. doi: 10.1186/1939-4551-8-S1-A267.
3. Cunningham-Rundles C. Common variable immune deficiency: case studies. Hematology Am Soc Hematol Educ Program. 2019;(1):449-56. doi: 10.1182/hematology.2019002062, PMID 31808912.
4. Daza Cajigal V, Segura Guerrero M, Lopez Cueto M, Robles Marhuenda A, Camara C, Gerra Galan T. Clinical manifestations and approach to the management of patients with common variable immunodeficiency and liver disease. Front Immunol. 2023;14:1197361. doi: 10.3389/fimmu.2023.1197361, PMID 37342345. Available from: https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.1197361
5. Franzblau LE, Fuleihan RL, Cunningham Rundles C, Wysocki CA. CVID-associated intestinal disorders in the USIDNET registry: an analysis of disease manifestations, functional status, comorbidities, and treatment. J Clin Immunol. 2023;44(1):32. doi: 10.1007/s10875-023-01604-6, PMID 38133694.