Author:
M GOPI SRIKANTH,N ARUNA DEVI,MOHAN C CHANDRA,K SOURIS,K MRUDHULA
Abstract
Epilepsy is among the commonly prevalent non communicable disease, particularly related to Central nervous system (CNS). The cumulative lifetime incidence of epilepsy is 3% and more than half of the cases begin in childhood. Seizures are common in pediatric age group and occur in approximately 10% of children. Epilepsyrequires long term anti-convulsanttreatment. The overall aim in the treatment of epilepsy should be complete control of seizures and no adverse reaction due to medication with an optimal quality of life. Epidemiological, clinical and experimental investigations have shown that anti- epileptic drugs (AED) predispose to atherosclerosis by altering the lipid profile.
Publisher
Innovare Academic Sciences Pvt Ltd
Subject
Pharmacology (medical),Pharmaceutical Science,Pharmacology
Reference11 articles.
1. World Health Organization. Epilepsy in the WHO African Region: Bridging the Gap. The Global Campaign against Epilepsy: “Out of the Shadows”. Geneva: WHO; 2004.
2. Muuronen A, Kaste M, Nikkila EA, Tolppanen EM. Mortality from ischemic heart disease among the patient using anticonvulsant drugs. Br Med J (Clin Res Ed) 1985;291:1481-3.
3. Johnston MV. Seizures in childhood. In: Kliegman R, Behrman R, Jenson H, Stanton B, editors. Nelson Textbook of Pediatrics. 19th ed. Philadelphia: WB Saunders; 1993.
4. Pack AM. SUDEP: What are the risk factors? Do seizures or antiepileptic drugs contribute to an increased risk? Epilepsy Curr 2012;12:131-2. doi: 10.5698/1535-7511-12.4.131, PMID 22936881
5. Prakash V, Mahto AK, Hussain S, Alam M. Comparative study of outcome of treatment of traumatic paraplegia by hartshill fixation vs pedicle screw fixation. J Med Sci Clin Res 2018;6:1235-43.