Risk Factors for Relapse of Human Brucellosis

Abstract

<p><strong>BACKGROUND &amp; PROPOSE: </strong>Brucellosis is serious disease around the world, especially in underdeveloped countries. It’s clinical manifestations is extensive.<strong> </strong>Thus diagnosis and treatment of this infection have difficulties, in among them, relapse is a great problem. This study aimed to evaluate risk factors of relapse after treatment in patients.</p><p><strong>METHODS: </strong>It is a descriptive-analytic study from 1990 to 2014, in Ayatolla Rohani hospital in Babol, Iran. We studied 980 patients with brucellosis. The studied community included patients infected with brucellosis and the required information was gathered based on their hospital files. The base for recognizing Malta fever were clinical symptoms and Para-clinical sign congruent with infection like as, titer SAT&gt;1:320 and 2-ME&gt;1:160. Patients with relapse and patients without relapse were placed separately in two groups. The data were statistically compared with Spss 16, by Chi-square and Cox –regression tests.</p><p><strong>RESULTS: </strong>Based on this study, treatment regimen is a preventive factor (P=0.000). Moreover, Based on some statistical methods, regimens no. 3 and 4 were introduce preventive factors (P=0.001) and (P=0.004). It should also be noted that findings the same statistical model, factors like gender, age, residence, professional contacts, complications and delay in treatment were also analyzed but none of them are considered as preventive factors<strong>.</strong></p><p><strong>CONCLUSION: </strong>Since the main and exact reason for Malta fever’ relapse is not recognized yet, anticipation of relapse is beneficent for treatment of infection.</p>