INVESTIGATIONS ON THE OCCURRENCE OF Rh SUBSTANCES IN AMNIOTIC FLUID

Author:

Witebsky Ernest1,Mohn James F.1,

Affiliation:

1. From the Laboratories of The Buffalo General Hospital, and the Department of Bacteriology and Immunology, University of Buffalo School of Medicine, Buffalo

Abstract

1. Rh substances are found in amniotic fluid. Not all anti-Rh sera seem to be suitable for the detection of Rh substances in amniotic fluid. Careful selection of Rh antisera, as well as quantitative considerations, determine success or failure of their demonstration. 2. The baby's Rh type and not the mother's determines the occurrence of Rh substances in amniotic fluid. 3. There are Rh secretors and Rh non-secretors. At least four out of five individuals are secretors. 4. The secretion of Rh substance into the amniotic fluid would seem to be entirely independent of the secretion of the blood group specific substances. 5. The majority of Rh-positive amniotic fluids seem to contain both Rh1 and Rh2 substances. However, in certain instances fluids belonging to the pure Rh1 type or pure Rh2 type were found. 6. Three cases of erythroblastosis were described. All three came from Rh-negative mothers with Rh-positive babies. The amniotic fluids of all three failed to reveal the presence of Rh substances.

Publisher

Rockefeller University Press

Subject

Immunology,Immunology and Allergy

Cited by 30 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Amniocentesis;Clinics in Perinatology;1974-03

2. Group specificity of amniotic fluid in the early periods of pregnancy;Bulletin of Experimental Biology and Medicine;1969-04

3. ANTENATAL DETERMINATION OF FETAL BLOOD GROUPS;BJOG: An International Journal of Obstetrics and Gynaecology;1969-04

4. Diagnosis and Treatment of Erythroblastosis in the Fetus;Advances in Pediatrics;1968

5. Studies on the Rh (D) Antigen;Vox Sanguinis;1965-01-02

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