A STUDY OF THE ANTIGENICITY OF T3 AND T4 COLI-DYSENTERY BACTERIOPHAGES DURING THE VEGETATIVE STAGE OF DEVELOPMENT

Author:

Barry Guy T.1

Affiliation:

1. From the Laboratories of The Rockefeller Institute for Medical Research

Abstract

The development of viral neutralizing antibodies in animals injected with T3 or T4 phage is considerably inhibited by the presence of bacterial antigens. A new procedure has been described to liberate phage from infected E. coli B bacteria by inducing lysis with penicillin. By immunological means it has been shown that T4-infected cultures of E. coli B, in which phage development has been inhibited with proflavine, contain the viral neutralizing antigen after lysis. In contrast, it has not been possible to demonstrate by immunological means the appearance of viral neutralizing antigen in E. coli B infected with T3 prior to the appearance of intracellular phage.

Publisher

Rockefeller University Press

Subject

Immunology,Immunology and Allergy

Cited by 6 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Bacteriophage resistance in Escherichia coli K-12: general pattern of resistance;Journal of Bacteriology;1975-03

2. Serological grouping and thermal death points of S. virchow bacteriophages;Zeitschrift für Hygiene und Infektionskrankheiten;1959-11

3. Intracellular Multiplication of Bacterial Viruses;The Viruses;1959

4. Genetics of Microorganisms;Annual Review of Microbiology;1955-10

5. Comparative Biochemistry and Virology;Advances in Virus Research;1955

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