EFFECT OF PREPUBERTY CASTRATION ON SUBSEQUENT CANCER IMPLANTATION

Author:

Murphy James B.1,Sturm Ernest1

Affiliation:

1. From the Laboratories of The Rockefeller Institute for Medical Research.

Abstract

Male and female mice castrated during the first 7 weeks of life and implanted with cancer at later periods show a resistance definitely higher than do intact animals of the same age. This increased refractiveness is evident at 3 months after the operation but is more pronounced at 8 months to a year. Even castration in early adult life seems to increase the refractory state to later cancer inoculation. On the other hand, adult mice inoculated within a week after castration show slight if any evidence of increased resistance.

Publisher

Rockefeller University Press

Subject

Immunology,Immunology and Allergy

Cited by 21 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Ovarian Transplantation for the Treatment of Gonadal Anomalies;The Tohoku Journal of Experimental Medicine;1962

2. Physiologische Chemie der Lebensvorgänge und Organe (Fortsetzung);Der Stoffwechsel;1959

3. Ionizing Radiations and Cancer;Advances in Cancer Research;1954

4. Tumore Gastrico Sperimentale;Tumori Journal;1947-05

5. STUDIES ON PROSTATIC CANCER;Archives of Surgery;1941-08-01

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