PROPERTIES OF THE CAUSATIVE AGENT OF A CHICKEN TUMOR

Author:

Murphy James B.1,Sturm Ernest1,Claude Albert1,Helmer Oscar M.1

Affiliation:

1. From the Laboratories of The Rockefeller Institute for Medical Research

Abstract

By two methods a protein fraction can be separated out from a Chicken Tumor I extract, which carries all the tumor-producing agent. The precipitate can be dissolved and reprecipitated a number of times without loss of activity. The agent can be largely dissociated from the protein as shown by the fact that aluminum hydroxide will adsorb the protein from an extract and leave the agent behind. This purified material has a very low protein content, if any, as shown by both chemical and biological tests.

Publisher

Rockefeller University Press

Subject

Immunology,Immunology and Allergy

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