Author:
Vadas M A,Miller J F,McKenzie I F,Chism S E,Shen F W,Boyse E A,Gamble J R,Whitelaw A M
Abstract
The Ly and Ia phenotypes of T lymphocytes involved in different functions were characterized by the use of specific antisera. T cells responsible for delayed-type hypersensitivity (DTH) and for helper functions were found to be Ly-1+,2- in contrast to cytotoxic T cells and T cells responsible for suppression of antibody responses which were Ly-1-,2+. Unlike some primed helper cells, T cells involved in DTH were Ia-. Suppressor cells in the system were Ia+.
Publisher
Rockefeller University Press
Subject
Immunology,Immunology and Allergy
Cited by
204 articles.
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