CELL-BOUND RECEPTORS FOR ALLOANTIGENS ON NORMAL LYMPHOCYTES-Reference-Cited by-同舟云学术

CELL-BOUND RECEPTORS FOR ALLOANTIGENS ON NORMAL LYMPHOCYTES

Published:1974-09-01 Issue:3 Volume:140 Page:731-741
ISSN:1540-9538
Container-title:Journal of Experimental Medicine
language:en
Short-container-title:

Author:

Binz Hans¹,Lindenmann Jean¹,Wigzell Hans¹

Affiliation:

1. From the Department of Experimental Microbiology, Institute for Medical Microbiology, University of Zürich, Zürich, Switzerland, and the Department of Immunology, Uppsala University Medical School, Uppsala, Sweden

Abstract

The rat popliteal node graft-vs.-host assay was shown to depend on the presence of parental T cells in the inoculum. Antialloantisera raised in F1 hybrid rats against alloantibodies of one parent directed at transplantation antigens of the other parent displayed some or all of the following specific effects on parental T cells: They inhibited local GvH by purified T-cell suspensions; they blocked the capacity of GvH-reactive cells to adsorb onto fibroblast monolayers of the relevant genotype; together with complement, they killed GvH-reactive cells.

Publisher

Rockefeller University Press

Subject

Immunology,Immunology and Allergy

Link

http://rupress.org/jem/article-pdf/140/3/731/1086458/731.pdf

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