Immune system: The “seventh sense”-Reference-Cited by-同舟云学术

Immune system: The “seventh sense”

Published:2018-01-16 Issue:2 Volume:215 Page:397-398
ISSN:0022-1007
Container-title:Journal of Experimental Medicine
language:en
Short-container-title:

Author:

Kipnis Jonathan¹^ORCID

Affiliation:

1. Department of Neuroscience, Center for Brain Immunology and Glia (BIG), School of Medicine, University of Virginia, Charlottesville, VA

Abstract

The brain is our computing machine that integrates stimuli from the environment and orchestrates responses to these stimuli. Here, I propose that the defining role of the immune system is to sense microorganisms and to inform the brain about them.

Funder

National Institutes of Health

Publisher

Rockefeller University Press

Subject

Immunology,Immunology and Allergy

Link

http://rupress.org/jem/article-pdf/215/2/397/1170346/jem_20172295.pdf

Reference15 articles.

1. IL-17 is a neuromodulator of Caenorhabditis elegans sensory responses

2. Twenty years of research on cytokine-induced sickness behavior

3. Regulation of learning and memory by meningeal immunity: a key role for IL-4

4. Unexpected role of interferon-γ in regulating neuronal connectivity and social behaviour

5. Central Administration of Lipopolysaccharide Induces Depressive-like Behavior in Vivo and Activates Brain Indoleamine 2,3 Dioxygenase In Murine Organotypic Hippocampal Slice Cultures

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