CD19-directed T cell–engaging antibodies for the treatment of autoimmune disease-Reference-Cited by-同舟云学术

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CD19-directed T cell–engaging antibodies for the treatment of autoimmune disease

Published:2024-04-08 Issue:5 Volume:221 Page:
ISSN:0022-1007
Container-title:Journal of Experimental Medicine
language:en
Short-container-title:

Author:

Michaelson Jennifer S.¹^ORCID,Baeuerle Patrick A.¹²^ORCID

Affiliation:

1. Cullinan Oncology, Inc. 1 , Cambridge, MA, USA

2. Institute for Immunology, Ludwig Maximilians University 2 , Munich, Germany

Abstract

Jennifer S. Michaelson, Chief Scientific Officer at Cullinan Oncology, and Patrick A. Baeuerle, scientific advisor to Cullinan Oncology and honorary professor in immunology at Ludwig Maximilians University Munich, discuss the use of CD19-specific T cell–engaging antibody therapies (TCEs) as therapeutics for autoimmune diseases.

Publisher

Rockefeller University Press

Link

https://rupress.org/jem/article-pdf/doi/10.1084/jem.20240499/1927108/jem_20240499.pdf

Reference14 articles.

1. Autoimmune disease is the next frontier for CAR T cell therapy

2. Targeting B Cells and Antibody in Transplantation

3. Bispecific antibodies for the treatment of B-cell lymphoma: promises, unknowns, and opportunities

4. Engineered cellular immunotherapies in cancer and beyond

5. Double Step-up Dosing (2SUD) Regimen Mitigates Severe Icans and CRS While Maintaining High Efficacy in Subjects with Relapsed/Refractory (R/R) B-Cell Non-Hodgkin Lymphoma (NHL) Treated with AZD0486, a Novel CD19xCD3 T-Cell Engager (TCE): Updated Safety and Efficacy Data from the Ongoing First-in-Human (FIH) Phase 1 Trial

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