Stress relief of chemo illness-Reference-Cited by-同舟云学术

Stress relief of chemo illness

Published:2024-05-06 Issue:7 Volume:221 Page:
ISSN:0022-1007
Container-title:Journal of Experimental Medicine
language:en
Short-container-title:

Author:

Rose Adam J.¹^ORCID,Lockie Sarah H.²^ORCID

Affiliation:

1. Biomedicine Discovery Institute, Monash University 1 Nutrient Metabolism and Signalling Laboratory, Department of Biochemistry and Molecular Biology, Metabolism, Diabetes and Obesity Program, , Melbourne, Australia

2. Biomedicine Discovery Institute, Monash University 2 Appetite and Behavioural Control Group, Department of Physiology, Metabolism, Diabetes and Obesity Program, , Melbourne, Australia

Abstract

New studies (Tang et al. 2024. J. Exp. Med.https://doi.org/10.1084/jem.20231395) describe a liver stress pathway that is activated by certain chemotherapeutic drugs, which in turn induces a peptide hormone which partially mediates the lower food intake and body weight loss during chemotherapy treatment.

Funder

National Health and Medical Research Council of Australia

Diabetes Australia Research Program

National Institutes of Health

Publisher

Rockefeller University Press

Link

https://rupress.org/jem/article-pdf/doi/10.1084/jem.20240545/1927829/jem_20240545.pdf

Reference17 articles.

1. GDF-15 Neutralization Alleviates Platinum-Based Chemotherapy-Induced Emesis, Anorexia, and Weight Loss in Mice and Nonhuman Primates

2. The GDF15-GFRAL axis mediates chemotherapy-induced fatigue in mice

3. The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule

4. IRE1A Stimulates Hepatocyte-Derived Extracellular Vesicles That Promote Inflammation in Mice With Steatohepatitis

5. Chemotherapy-Induced Nausea and Vomiting: Pathogenesis, Recommendations, and New Trends