Author:
Bettelli Estelle,Kuchroo Vijay K.
Abstract
Traditionally, CD4+ T cells have been separated into two different subsets named T helper (Th)1 and Th2. A new IL-23–driven subset of Th cells called ThIL-17 has now been described. The data suggest that IL-23 plays an important role in the differentiation of autoreactive pathogenic T cells. Whether these IL-23–induced ThIL-17 cells are a unique subset or are related to other Th subsets is discussed.
Publisher
Rockefeller University Press
Subject
Immunology,Immunology and Allergy
Cited by
125 articles.
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