ISOLATION OF CHROMATIN THREADS FROM THE RESTING NUCLEUS OF LEUKEMIC CELLS

Author:

Claude Albert1,Potter James S.1

Affiliation:

1. From the Laboratories of The Rockefeller Institute for Medical Research, New York, and the Department of Genetics, Carnegie Institution of Washington, Cold Spring Harbor

Abstract

1. A method for the separation of chromatin threads from the resting nucleus of leukemic cells has been described. 2. The isolation of the chromatin strands was accomplished by purely mechanical means, and the separation, including extraction and purification in the centrifuge, required only about 1 hour. 3. Evidence is presented to show that the chromatin strands are morphologically related to the chromosomes, if not identical. 4. It seems probable that, by the present technique, chromatin strands can be obtained from different mammalian tissues for direct microscopical examination and biochemical analysis.

Publisher

Rockefeller University Press

Subject

Immunology,Immunology and Allergy

Cited by 77 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Biological Energy Transformations and the Cancer Problem;Advances in Enzymology - and Related Areas of Molecular Biology;2006-11-22

2. The Chemistry of the Cell Nucleus;Advances in Enzymology - and Related Areas of Molecular Biology;2006-11-22

3. Principles of Enzymic Histo- and Cytochemistry;Advances in Enzymology - and Related Areas of Molecular Biology;2006-11-22

4. Isolation and extraction of nuclei, chromosomes and chromosome components;Chromosome Techniques;1980

5. TISSUE FRACTION-PAST AND PRESENT;Journal of Cell Biology;1971-07-01

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3