Affiliation:
1. From the Department of Pediatrics, State University of New York, Downstate Medical Center, Brooklyn
Abstract
The effect of homograft sensitization of a mother against her fetuses has been studied. A female rabbit was repeatedly grafted from both members of a breeding pair. Their offspring should and do become objects of homograft sensitization induced in the female by grafts from the parents. After sensitization was established, fertilized ova were transplanted from the breeding pair to the sensitized female. At the same operation, an equal number of eggs was also transplanted to the same recipient from another breeding pair against which no sensitization had been induced. In 16 such families, the survival rates for offspring born of each type of egg were found to be almost identical, indicating that homograft sensitization in the mother directed against her fetuses did not demonstrably harm them.
Publisher
Rockefeller University Press
Subject
Immunology,Immunology and Allergy
Cited by
20 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献