Affiliation:
1. Patricia and John Rosenwald Laboratory of Neurobiology and Genetics, The Rockefeller University, New York, NY
Abstract
Plasminogen and its active form, plasmin, have diverse functions related to the inflammatory response in mammals. Due to these roles in inflammation, plasminogen has been implicated in the progression of a wide range of diseases with an inflammatory component. In this review, we discuss the functions of plasminogen in inflammatory regulation and how this system plays a role in the pathogenesis of diseases spanning organ systems throughout the body.
Funder
National Institutes of Health
Cure Alzheimer’s Fund
Alzheimer’s Association
Alzheimer's Drug Discovery Foundation
Samuel I. Newhouse Foundation
Rudin Family Foundation
Publisher
Rockefeller University Press
Subject
Immunology,Immunology and Allergy
Cited by
79 articles.
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