IMMUNOCHEMICAL STUDIES ON BLOOD GROUPS

Author:

Feizi Ten1,Kabat Elvin A.1

Affiliation:

1. From the Departments of Microbiology, Neurology, and Human Genetics and Development, College of Physicians and Surgeons, Columbia University; the Neurological Institute, Presbyterian Hospital, New York 10032; and the Rockefeller University, New York 10021

Abstract

Quantitative precipitin assays were carried out with eleven anti-I and five anti-i cold agglutinin sera. Their reaction patterns with precursor substances and with certain antigens related to the A, B, H, Lea, and Leb substances revealed at least six types of I and four types of i specificity. All of the I and i determinants appear to be represented in varying amounts on that fraction of the ovarian cyst precursor substance OG which was precipitated by 20% ethanol (OG 20% 2X). Only some of these determinants can be detected in the first periodate oxidation stages of A, B, and H substances, in cow substances, and in hydatid cyst fluid.

Publisher

Rockefeller University Press

Subject

Immunology,Immunology and Allergy

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