STUDIES ON THE ULTRASTRUCTURE OF BORDETELLA PERTUSSIS

Author:

Morse Jane H.1,Morse Stephen I.1

Affiliation:

1. From the Department of Medicine, Columbia University, College of Physicians and Surgeons, New York 10032 and the Department of Microbiology and Immunology, State University of New York, Downstate Medical Center, Brooklyn, New York 11203

Abstract

Two distinct particles have been recognized in the extracellular fluid of B. pertussis cultures. Both appeared to arise from the surface (cell wall) of the organism. One of these, a membranous particle, seemed to derive from long projections on the organism composed of the outer membrane of the cell wall. The second particle, a fine filament, was not readily comparable with any previously described bacterial structure. The two particles could be separated from each other by gradient centrifugation in CsCl. Lymphocytosis-promoting factor and histamine-sensitizing activity were only associated with fractions containing the fine filaments.

Publisher

Rockefeller University Press

Subject

Immunology,Immunology and Allergy

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1. Bordetella pertussis and outer membrane vesicles;Pathogens and Global Health;2022-09-01

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