1. Department of Biomedical Sciences, Humanitas University 1 , Pieve Emanuele, Italy
2. Tumor microenvironment unit, IRCCS Humanitas Research Hospital 2 , Rozzano, Italy
3. Oncology Unit, Humanitas Gavazzeni 3 , Bergamo, Italy
4. Department of Biomedical Sciences, Humanitas University 4 , , Rozzano, Italy
5. Pieve Emanuele, Italy; IRCCS Humanitas Research Hospital 4 , , Rozzano, Italy
6. William Harvey Research Institute 5 , , London, UK
7. Queen Mary University 5 , , London, UK