THE RELATION OF HERPES VIRUS TO HOST CELL MITOCHONDRIA-Reference-Cited by-同舟云学术

THE RELATION OF HERPES VIRUS TO HOST CELL MITOCHONDRIA

Published:1952-08-01 Issue:2 Volume:96 Page:151-157
ISSN:1540-9538
Container-title:Journal of Experimental Medicine
language:en
Short-container-title:

Author:

Ackermann W. Wilbur¹,Kurtz Hilda¹

Affiliation:

1. From the Department of Epidemiology and Virus Laboratory, School of Public Health, University of Michigan, Ann Arbor

Abstract

The intracellular distribution of herpes virus in embryonic liver was investigated. 80 per cent of the virus was found in the cytoplasm in what appears to be a form uncombined with mitochondria or nuclei. A significant amount of the virus (16 per cent) was found bound to the mitochondria by an intimate attachment. Furthermore evidence was obtained that the mitochondria from liver tissue undergo a selective deterioration when infected with herpes virus. The concept is advanced that these organelles function in the development of virus.

Publisher

Rockefeller University Press

Subject

Immunology,Immunology and Allergy

Link

http://rupress.org/jem/article-pdf/96/2/151/1184926/151.pdf

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