Affiliation:
1. From the Division of Laboratories and Research, New York State Department of Health, Albany
Abstract
An alteration of tissue tropism of a Coxsackie virus has been observed following different methods of propagation of the virus in animals.
Tropism for the adult mouse pancreas, as described by Pappenheimer, appeared to be irrevocably lost following prolonged brain-to-brain transfer.
It was present in the same strain on reisolation from human feces, was intensified following pancreas transfers, and suppressed by brain transfers.
Pancreatotropism may be correlated with the titer of virus in the pancreas.
Publisher
Rockefeller University Press
Subject
Immunology,Immunology and Allergy
Cited by
30 articles.
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