Affiliation:
1. From The Rockefeller University, New York 10021
Abstract
Specific binding of aggregated γ-globulin to a subpopulation of lymphocytes was demonstrated. This subpopulation was identified as the Ig-staining or B lymphocytes. The binding was irreversible and independent of complement, pH, temperature, protein content of the medium, and divalent cations. Aggregates of large size were needed for optimal visualization. Evidence was obtained that the site on the lymphocyte membrane responsible for binding aggregates was distinct from surface Ig.
Publisher
Rockefeller University Press
Subject
Immunology,Immunology and Allergy
Cited by
591 articles.
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