Affiliation:
1. Department of Immunology, University of Stockholm, Sweden.
Abstract
Erythrocytes infected with trophozoites or schizonts of Plasmodium falciparum bind uninfected erythrocytes, leading to rosette formation. Both established laboratory strains and fresh isolates from patients form such rosettes, but at widely different frequencies. IgG preparations from the serum of some P. falciparum-immune donors and heparin inhibited rosette formation. The results indicate that cytoadherence of infected erythrocytes to endothelial cells and rosetting represent distinct genetic traits.
Publisher
Rockefeller University Press
Subject
Immunology,Immunology and Allergy
Cited by
193 articles.
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