THE COEXISTENCE OF PROTOZOAN-LIKE PARASITES AND MENINGOENCEPHALITIS IN MICE

Author:

Cowdry E. V.1,Nicholson F. M.1

Affiliation:

1. From the Laboratories of The Rockefeller Institute for Medical Research.

Abstract

A small proportion of laboratory mice, which appear to be normal, are in reality suffering from an obscure disease characterized by the presence of marked meningoencephalitic lesions which are often accompanied by protozoan-like parasites. Both the lesions and the parasites closely resemble others previously reported in rabbits, which likewise fail to reveal themselves by pronounced clinical symptoms. In the absence of direct experimental evidence it is suggested either that one species of parasite is capable of producing the lesions in both animals, or else that we have to do with two kinds of parasites which are closely related and, in the stages thus far observed, are indistinguishable one from the other.

Publisher

Rockefeller University Press

Subject

Immunology,Immunology and Allergy

Cited by 15 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Immunologic and clinicopathologic evaluation of adult dogs inoculated with Encephalitozoon cuniculi;Journal of Clinical Microbiology;1988-03

2. The effect of congenital and adult-acquiredToxoplasmainfections on the motor performance of mice;Annals of Tropical Medicine & Parasitology;1983-06

3. The Nervous System;Pathology of Laboratory Animals;1978

4. Normal Range and Variability of Hematologic and Blood-Chemical Parameters from Beagle Dogs and Rhesus Monkeys;The Bulletin of the Society of Pharmacological and Environmental Pathologists;1974-09

5. The History of Two Monogamously Paired Mouse Colonies at Brookhaven National Laboratories;The Bulletin of the Society of Pharmacological and Environmental Pathologists;1974-09

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