Affiliation:
1. From the National Institute for Medical Research, Hampstead, London
Abstract
A strain of rabbit fibroma is described causing in inoculated animals acute inflammatory lesions very different from the fibroma-like growths induced by the original strain. The new inflammatory strain cross-immunised with the normal strain but not with various other viruses. Efforts at changing one strain into the other were unsuccessful. Another, referred to as the changed, strain produced lesions of mixed character, partly inflammatory, partly fibromatous; it continued to behave in this way through numerous passages. An artificial mixture of inflammatory and fibromatous viruses behaved in all respects like the changed strain. Discussion of the significance of the findings is reserved for a separate paper (3) where the facts can be considered in relation to those described by Shope (2).
Publisher
Rockefeller University Press
Subject
Immunology,Immunology and Allergy
Cited by
49 articles.
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1. Viral Diseases;The Laboratory Rabbit, Guinea Pig, Hamster, and Other Rodents;2012
2. THE INFLUENCE OF »MUCIN 1701 W« ON INFECTION WITH SHOPE FIBROMA AND VACCINIA VIRUSES.;Acta Pathologica Microbiologica Scandinavica;2009-08-17
3. THE INFLUENCE OF »MUCIN 1701 W« ON INFECTION WITH SHOPE FIBROMA AND VACCINIA VIRUSES.;Acta Pathologica Microbiologica Scandinavica;2009-08-10
4. Viral Diseases;The Biology of the Laboratory Rabbit;1994
5. OVATOOMB: Other viruses and the origins of molecular biology;Journal of the History of Biology;1993