IMMUNOHISTOCHEMICAL DEMONSTRATION OF IgG IN REED-STERNBERG AND OTHER CELLS IN HODGKIN'S DISEASE-Reference-Cited by-同舟云学术

IMMUNOHISTOCHEMICAL DEMONSTRATION OF IgG IN REED-STERNBERG AND OTHER CELLS IN HODGKIN'S DISEASE

Published:1974-05-01 Issue:5 Volume:139 Page:1077-1083
ISSN:1540-9538
Container-title:Journal of Experimental Medicine
language:en
Short-container-title:

Author:

Garvin A. J.¹,Spicer S. S.¹,Parmley R. T.¹,Munster A. M.¹

Affiliation:

1. From the Departments of Pathology and Surgery, Medical University of South Carolina, Charleston, South Carolina 29401

Abstract

Spleens and lymph nodes fixed lightly for optimal immunocytochemistry or processed routinely for surgical diagnosis disclosed strong selective immunostaining for IgG in numerous immunocytes in tumor-free areas. Areas involved by Hodgkin's disease revealed, in addition, strong immunostaining for IgG but not IgM in Reed-Sternberg cells and faint to strong staining in Hodgkin cells as well. Ultrastructurally the Reed-Sternberg and Hodgkin cells displayed abundant polyribosomes and sparse granular reticulum and appeared to form unexportable IgG on unbound ribosomes.

Publisher

Rockefeller University Press

Subject

Immunology,Immunology and Allergy

Link

http://rupress.org/jem/article-pdf/139/5/1077/1085942/1077.pdf

Cited by 127 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Bioinformatics analysis of whole slide images reveals significant neighborhood preferences of tumor cells in Hodgkin lymphoma;PLOS Computational Biology;2020-01-21

2. The Elusive Hodgkin Cell;Scandinavian Journal of Haematology;2009-04-24

3. Evidence for the detection of the normal counterpart of hodgkin and sternberg-reed cells;Hematological Oncology;2007-11-02

4. Molecular morphology of Hodgkin lymphoma;Applied Immunohistochemistry;2001-09-01

5. Molecular Morphology of Hodgkin Lymphoma;Applied Immunohistochemistry & Molecular Morphology;2001-09