THE RELATIVE PREVALENCE OF HUMAN AND BOVINE TYPES OF TUBERCLE BACILLI IN BONE AND JOINT TUBERCULOSIS OCCURRING IN CHILDREN

Author:

Fraser John1

Affiliation:

1. From the Research Laboratory of the Royal College of Physicians, Edinburgh.

Abstract

The all important point revealed by the investigation is the fact that a large proportion of bone and joint tuberculosis occurring in children in Edinburgh owes its origin to infection by the bovine bacillus. The bovine bacillus is introduced into the system practically by one route only, that of ingestion, and the medium with which it is ingested is cow's milk. It is not my intention to criticize in any way the existing conditions of milk supply. I have furnished proof of what is actually occurring and no one will deny that the evil is a remediable one. In those cases in which the human bacillus was present, a considerable proportion showed a definite history of pulmonary tuberculosis affecting a co-resident, and every fact went to prove that the infection had been a direct one from patient to child. A complete distinction can be drawn between human and bovine bacilli, and the distinction is best secured by subjecting the organism to a series of tests such as I have detailed. The subject is one which ought to be investigated in a series of different localities. It is possible that the locus may be a factor in the explanation of the difference between the above results and those of other observers.

Publisher

Rockefeller University Press

Subject

Immunology,Immunology and Allergy

Cited by 16 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Scotland: The changes of the years;British Journal of Tuberculosis and Diseases of the Chest;1956-01

2. A survey of tuberculosis in the industrial county of Lanarkshire, Scotland;Journal of Hygiene;1947-05

3. STUDIES IN TUBERCULOSIS;Medical Journal of Australia;1941-07

4. PATHOLOGY AND BACTERIOLOGY;The American Journal of the Medical Sciences;1939-03

5. VIII. Tuberculous Dactylitis;Medical Journal of Australia;1938-07

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