Affiliation:
1. From the Department of Pathology, The New York Hospital-Cornell Medical Center, and The Department of Microbiology, New York University College of Medicine, New York
Abstract
All enzyme that destroys DPN has been found in fractionated and highly concentrated streptococcal preparations that also contain streptolysin O. The enzyme—streptococcal DPNase—was shown by electrophoretic separation and by other means to be distinct from streptolysin O. It is non-dialyzable, heat-labile, and has optimal activity in the pH range 7.2 to 7.8. The enzyme has a high degree of specificity for DPN, which it splits at the nicotinamide-ribose linkage.
Publisher
Rockefeller University Press
Subject
Immunology,Immunology and Allergy
Cited by
71 articles.
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