THE FUNCTION OF THE KIDNEY WHEN DEPRIVED OF ITS NERVES

Author:

Quinby William C.1

Affiliation:

1. From the James B. Brady Urological Institute, Johns Hopkins Hospital, Baltimore.

Abstract

1. By means of vascular suture it is possible to remove the dog's kidney from the body and later to restore it to its former position. 2. Such a kidney is removed from the control of the nervous system, at least for a time. 3. Examination of the function of a kidney so treated shows an initial period of overaction, as compared with that of the normal kidney. 4. This is followed by balanced action. 5. The more recent tests of renal function show that a single, reimplanted kidney is able to maintain normal life indefinitely. 6. The results of these experiments, together with the evidence already at hand, suggest strongly that secretory nerves to the kidney do not exist.

Publisher

Rockefeller University Press

Subject

Immunology,Immunology and Allergy

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2. Transplant Tolerance: New Insights and Strategies for Long-Term Allograft Acceptance;Clinical and Developmental Immunology;2013

3. Renal Denervation for Hypertension;JACC: Cardiovascular Interventions;2012-03

4. The first successful organ transplants in man;Journal of the American College of Surgeons;2005-01

5. Neural control of renal function;Physiological Reviews;1997-01-01

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