A TYPE-SPECIFIC PROTEIN FROM PNEUMOCOCCUS

Author:

Austrian Robert1,MacLeod Colin M.1

Affiliation:

1. From the Department of Microbiology, New York University College of Medicine, New York

Abstract

The isolation and characterization of a type-specific M protein from pneumococcus are described. This protein is similar chemically in all respects studied to the M proteins of group A streptococci. No immunological crossreactions have been observed, however, between M proteins of the two species. Strains of capsular type I pneumococcus have been encountered which contain different M proteins. The same is true for capsular type II pneumococcus. It is apparent, therefore, that the capsular polysaccharides and M proteins can vary independently of each other.

Publisher

Rockefeller University Press

Subject

Immunology,Immunology and Allergy

Cited by 44 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Choline-Binding Proteins;The Pneumococcus;2014-04-30

2. Die Immunisierung trächtiger Rinder gegen Pneumokok-ken-Polysaccharide und die biologische Bedeutung der im Kolostrum ausgeschiedenen spezifischen Antikörper;Zentralblatt für Veterinärmedizin;2010-05-13

3. Zur Frage der Erfassung und Charakterisierung der Dissoziationsformen von Brucella abortus*;Zentralblatt für Veterinärmedizin;2010-05-13

4. IMMUNODIFFUSION STUDIES OF PNEUMOCOCCAL ANTIGENS WITH SPECIAL REFERENCE TO SEROTYPE 27;Acta Pathologica Microbiologica Scandinavica Section B Microbiology and Immunology;2009-08-15

5. Pneumococcal Disease;Infectious Diseases in Clinical Practice;2004-03

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