A METHOD FOR COUPLING PROTEIN ANTIGENS TO ERYTHROCYTES

Author:

Cole Leon R.1,Matloff J. Jay1,Farrell Virginia R.1

Affiliation:

1. From the Departments of Medicine, Peter Bent Brigham Hospital, and Harvard University Medical School, and the Departments of Medicine, Boston City Hospital, and Boston University Medical School, Boston

Abstract

A serological technique, using formalinized red cells coupled to tuberculin PPD as antigen, has been assayed in a trial series of 124 tuberculous and 139 non-tuberculous patients. The stability of the antigen preparation, and the omission of an adsorption procedure for the removal of isoagglutinins facilitated the performance of the test. The results indicate that the technique warrants further trial as a diagnostic criterion of infection tuberculosis.

Publisher

Rockefeller University Press

Subject

Immunology,Immunology and Allergy

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