Affiliation:
1. From the Institute for Medical Research, Cedars of Lebanon Hospital, Los Angeles, and the Hoagland Laboratory, the Department of Pathology of the College of Medicine at the State University Medical Center, New York
Abstract
Intraperitoneal administration of bovine albumin sharply increases glomerular permeability to hemoglobin in the rat kidney. In addition, bovine albumin "saturates" the tubular absorption mechanism and inhibits the tubular absorption of subsequently administered hemoglobin. Egg white, ovalbumin, and ovomucoid, in contrast, do not produce significant changes in glomerular permeability to hemoglobin or in the tubular absorption of hemoglobin. These effects have been demonstrated both by physiologic measurements and by the morphologic demonstration of the absorbed proteins.
Publisher
Rockefeller University Press
Subject
Immunology,Immunology and Allergy
Cited by
34 articles.
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