Affiliation:
1. Departamento de Bioquímica, Facultad de Medicina de la UAM, Spain.
Abstract
Sera from patients with systemic lupus erythematosus contain specific autoantibodies directed against different polypeptide components of the multicatalytic proteinase (also known as proteasome or prosome). These human autoantibodies, in contrast to polyclonal antibodies obtained in rabbits against the purified enzyme, recognize highly conserved epitopes of the multicatalytic proteinase polypeptides from yeast to human.
Publisher
Rockefeller University Press
Subject
Immunology,Immunology and Allergy
Cited by
33 articles.
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