Sendai virus-specific T cell clones. V. Induction of a virus-specific response by antiidiotypic antibodies directed against a T helper cell clone.

Author:

Ertl H C,Homans E,Tournas S,Finberg R W

Abstract

We used an antiidiotypic antibody directed against a Sendai virus-specific T helper cell clone to stimulate an immune response in vivo. In addition, the antiidiotypic antibody induced T cells that mediated a delayed-type hypersensitivity (DTH) response in several different mouse strains. Induction of the DTH response by the antiidiotypic antibody, in contrast to the DTH responses induced by virus, demonstrated a remarkable lack of H-2 restriction.

Publisher

Rockefeller University Press

Subject

Immunology,Immunology and Allergy

Cited by 37 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Idiotypes;eLS;2011-11-15

2. Monoclonal Antibodies Specific for Sendai Virus;Scandinavian Journal of Immunology;2006-06-29

3. Studies of Monoclonal Antibodies Specific for Major Histocompatibility Complex Products of the Rat;Scandinavian Journal of Immunology;2006-06-29

4. IMMUNOGLOBULIN VARIABLE REGIONS AS IDIOTYPE VACCINES;Infectious Disease Clinics of North America;1999-03

5. The Perpetual Network Theory and its Putative Applications: 21 Years Later;Idiotypes in Medicine: Autoimmunity, Infection and Cancer;1997

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