Abstract
The aim of the study was to study the interrelation between clinical, medical, biological and neurocognitive characteristics of maladaptation (as a component of pathopersonological transformations) in patients with schizoaffective
disorder in remission. On the basis of the Regional Clinical
Psychiatric Hospital (Zaporizhzhia, Ukraine) 102 persons with the established diagnosis of “schizoaffective disorder” were examined. Diagnosis
was per formed according to the International ICD-10. The mandatory
criteria for inclusion in the study were the presence of a condition of clinical
remission with reduction of psychotic symptoms and the absence of severe
somatic and neurological pathology, abuse of psychoactive substances.
The main methods of the study were clinical psychopathological, psychodiagnostical, clinical-anamnestic and clinical-cathamnestic as well as medi cal
and statistical analysis. The study established the presence
and regularities of conjugation of clinical, medical, biological, and neurocognitive characteristics of maladaptation (as a component of pathopersonological
transformations) in patients with schizoaffective disorder in remission.
The structure of neurocognitive deficits in schizoaffective disorder in remission is related to the clinical type of the disease, the sex, the duration
of the pathological process, and the characteristics of psychopharmacological
treatment. The established regularities emphasize the importance of neurocognitive disorders in the structure of pathopersonological transformations and can
be used in the formation of the system of diagnostic and treatment and rehabilitation measures to improve the quality of differential diagnosis and to carry out
preventive and therapeutic rehabilitation measures to reduce the level of social
maladaptation of patients with schizoaffective disorder.
Keywords: schizoaffective disorder, clinic, neurocognition, social maladaptation, pathopersonalogical transformations
Publisher
Public Organization Association of Neurologists, Psychiatrists and Narcologists of Ukraine
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