Fibrous Dysplasia-Reference-Cited by-同舟云学术

Fibrous Dysplasia

Published:2013-01-01 Issue:1 Volume:137 Page:134-138
ISSN:1543-2165
Container-title:Archives of Pathology & Laboratory Medicine
language:en
Short-container-title:

Author:

Riddle Nicole D.¹,Bui Marilyn M.¹

Affiliation:

1. From the Department of Pathology and Laboratory Medicine, Pennsylvania Hospital, Philadelphia (Dr Riddle); and the Department of Anatomic Pathology, Moffitt Cancer Center Hospital, Tampa, Florida (Dr Bui).

Abstract

Fibrous dysplasia is an uncommon bone disease. The diagnosis is usually not difficult, given the symptoms, radiology, and histology. The gene involved is the α subunit of the G-protein receptor. Recent innovation in molecular pathology has helped us understand the mechanism of disease pathogenesis. The treatment of fibrous dysplasia is limited to maintenance of maximum bone density. Surgical reinforcement is used to treat bowing deformities and fractures as they occur. Malignant transformation of fibrous dysplasia is rare. Currently, there is no therapy for preventing the disease from advancing or for malignant transformation.

Publisher

Archives of Pathology and Laboratory Medicine

Subject

Medical Laboratory Technology,General Medicine,Pathology and Forensic Medicine

Link

http://meridian.allenpress.com/aplm/article-pdf/137/1/134/1611125/arpa_2012_0013-rs.pdf

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