Comorbid patient: an interdisciplinary problem (literature review).

Abstract

The comorbidity of arterial hypertension (AH), type 2 diabetes mellitus (T2DM), obesity leads to the early development of atherosclerotic lesions of coronary and cerebral vessels, which, in turn, significantly accelerates the occurrence of coronary arterial disease (CHD), vascular disasters, namely, myocardial infarction (MI), stroke. Comorbidity fully refers to the concept of “metabolic syndrome”. By definition, metabolic syndrome (MS) is a complex of interrelated clinical, metabolic and hormonal disorders caused by the dysregulation of various genes, the influence of external environmental factors, associated with increased cardiovascular risk, and an increase in overall mortality. The article is intended to review modern scientific literature on metabolic syndrome and comorbid conditions associated with it.