Author:
Marunych R.Yu., ,Gornytska O.V.,Gudzenko A.V.,Salnyk O.A.,Hrabovskyi A.O.,Bereznytskyj G.K.,Makogonenko Ye.M., , , , , ,
Abstract
The structure and functions of the endothelium under normal conditions and a number of pathologies are reviewed in this work with the focus on its role in maintaining the balance between pro- and anticoagulant function of blood in different vascular beds. The role of endothelium in the synthesis and secretion of NO and other vascular regulators is highlighted. The mechanisms of its dysfunction, the role and interconnection of pathological changes in diseases such as atherosclerosis and hypertension are described.
Publisher
National Academy of Sciences of Ukraine (Co. LTD Ukrinformnauka)
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